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I took some prework out that had caffeine and a few other ingredients, one of which is yohimbine. For those who don't knoe yohimbine is a stimulant that acts on the adrenic receptors, basically releasing norepinephrine/the fught or flight neurotransmitter. I also took tagamet which is an anti acid. Little did i know that tagamet inhibits the enzyme in your body that breaks down yohimbine.
So while running I started to get hot flashes, sweating like crazy, and just tons of anxiety. I read up on the ingredients in my pre-workout supplement, and found those are side effects of too much yohimbine. Not only that but yohimbine is only supposed to last 1 to 2 hours, this lasted for 5 straight hours. I went to work after, and was shaking like crazy, and threw up 3 times. Add on too of that there was caffeine in that preworkout as well.
Tldr; I mixed an antiacid that stops a certain enzyme from breaking down yohimbine, a common stimulant used for fat burning, so essentially I got sick af. The lesson, please be careful when mixing preworkout with medication.
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